You can check the application memory on Mac at Activity Monitor. You can first try to reset the mouse pointer at the Accessibility feature, if it isn’t the matter, there are still some attempts that may work for you. This is regarded as a macOS bug, especially when you customize the mouse cursor color or size. Many Mac users encounter this problem after they upgraded the macOS to the latest Monterey version, and find the warning appears frequently even though they do nothing that eats so much system memory, for example, the Mail or Firefox app takes up gigabytes of the memory usage. It will keep asking your Mac for more space but never gives it back, which makes the system run out of application memory. When a program is using more and more space over time as it runs and fails to release memory, you can recognize it as a memory leak. If you have installed too many extensions, it’s time to manage them and delete some rarely used ones. But once opened, these extensions are running together with the browser even if not used, which take up a lot of space on Mac. We may install extensions and allow plugins in order to have a better browsing experience. To deal with this trouble, you can try some instant methods to get rid of it, but it’s recommended to manage your disk space for the long run. Or that you have lots of free disk space, but the currently running apps need such a large amount of virtual memory address space that macOS fails to provide. So, it takes up more and more memory until your hard drive is full and there is no room for the swap files, the system will report that it has run out of application memory. When running an app on Mac, if all physical RAM are used, macOS will create swap files, which takes up disk space. Reason 2: Your boot disk has little free space for running apps If that’s the cause, to quit or force quit the program may simply solve it.

It’s a common practice to run several apps on your Mac at the same time however, accumulation of excessive apps on the background will take up more and more space and finally leads to the problem of “system has run out of application memory”.

Reason 1: Too many apps run simultaneously There are four possible reasons account for the problem: When your Mac says system has run out of application memory, it means that your computer doesn't have enough memory required by applications to run. What Does System Has Run Out of Application Memory Mean?

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